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Common side effects of semaglutide include gastrointestinal side effects such as nausea, vomiting, diarrhea or constipation, abdominal pain, gas, and indigestion
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The drug primarily increases insulin secretion and decreases glucagon secretion in a glucose-dependent manner
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The widespread application of GLP-1 receptor agonists at the population level may impose significant financial pressure on pharmaceutical budgets, with modeling studies indicating that treating all eligible individuals with diabetes and obesity might need a 1020% rise in drug expenditures in several nations
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