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The pyroptotic process is typically initiated by recognition of pathogens in the cytosol or endogenous danger signals via inflammasomes, which recruit and activate inflammatory caspases such as caspase-1, -4, -5, -11 (160, 161)

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Research applications In research, MT-2 can be used as an experimental input for: Receptor pharmacology: comparing potency and efficacy across melanocortin receptor subtypes in cellular assays

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Zhang, X., Ren, W., Yang, C., Wang, L

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This component exerts its effects by activating the Nrf2 signaling pathway, reducing iron deposition, and enhancing antioxidant capacity (237)

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