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In particular, multi-omics approaches integrating metagenomics, metabolomics, and host transcriptomics may help elucidate the complex interactions between microbial metabolites and endocrinemetabolic pathways

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Without uridine, the cell compensates for pyrimidine shortage by over-activating ATP-consuming salvage pathways (UCK2, TK1, dCK), which potentially drives mitochondrial biogenesis to generate more ATP for these phosphorylation reactions 63

doi: 10.1016/j.jmb.2019.12.028 76 EshraghiMAdlimoghaddamAMahmoodzadehASharifzadFYasavoli-SharahiHLorzadehSet al

demonstrated that BPC-157 significantly accelerated Achilles tendon outgrowth and increased tendon fibroblast migration in a dose-dependent manner