Supplementary material The Supplementary Material for this article can be found online at: References 1 AbdelmasihR.SaeedZ.AshrafB.AbdelmaseihR.NasserH
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Retatrutide's proposed mechanism of action involves GLP-1 receptor activation to slow gastric emptying and promote satiety, GIP receptor activation to support insulin secretion and adipose tissue regulation, and glucagon receptor agonism, which in trial settings has been associated with increased energy expenditure and lipolysis
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