Nature 622 , 329338 (2023)
Adequate protein, ferritin above 70, vitamin D in the 5080 range, and a slower rate of loss all reduce severity
For context, the concentrations required to activate intracellular cascades such as PI3K/Akt, upregulate BDNF, or stimulate autophagy in neuronal tissue are derived from preclinical studies that used substantially higher relative exposures than those achievable in the human brain at therapeutic doses
By activating this pathway, researchers are studying its potential to increase energy expenditure and support the breakdown of stored fat, although further research is needed to understand the long-term impact
"FDA Approves First Treatment to Reduce Risk of Serious Heart Problems Specifically in Adults with Obesity or Overweight." SELECT trial: 20% reduction in major adverse cardiovascular events
Purposely, they are going to be obsessed with getting protein