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Based on these results, the OXPHOS perturbation-mediated improvement of immune response and hemocyte activation is at least partially independent of changes in ROS production

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doi: 10.1056/NEJMoa2032183 Garvey WT, Batterham RL, Bhatta M, et al

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But a potential downside of that is something called commonly the "Ozempic blahs." And what that is, is like a dulling out of the ups and downs in life, and sort of a lessening of the zest for life, including the zest for things that used to make them happy like gambling or smoking or drinking or partying