Despite the contradictory data regarding kidney outcomes, two surrogate outcomes benefit the most from combined therapy: the decline in eGFR slope and the reduction in urinary albumin-to-creatinine ratio
As an injectable treatment, semaglutide activates the bodys GLP-1 receptors
References Pooyandjoo M, Nouhi M, Shab-Bidar S, Djafarian K, Olyaeemanesh A
The clinical value of the blend depends on the patients medical history, symptoms, lifestyle, treatment goals, dosage and ability to follow the prescribed regimen
The simplest explanation may be that Semaglutide has a longer life-time and more favourable side-effect profile
Complementary neuroprotective effects of semaglutide and papaya in diabetic encephalopathy via antioxidant and insulin-signaling pathways