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doi:10.1056/NEJMoa1504720 5

The phenylarsenoxide group is the active moiety, imparting to GSAO its activity by crosslinking closely spaced protein thiols and forming a high affinity ring structure between its arsenic and the thiols (Donoghue et al., 2000)

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Case report evidence : The safety literature is dominated by case reports of serious harms including priapism, renal infarction, and melanoma in situ