The name was assigned by the original Zagreb research group to a 15-residue fragment of a larger cytoprotective protein found in human gastric juice (Sikiric et al., 2018)
Alongside banking, the group built Wells Fargo Asset Management, serving institutional and private clients
A common approach involves 2-4mg administered subcutaneously once daily
Relative contraindications requiring caution include active or suspected cancer (GHK-Cu promotes angiogenesis with concern about theoretically feeding tumors, though conflicting data shows documented anti-cancer gene expression effects requiring medical supervision), severe organ dysfunction (kidney or liver failure may slow peptide clearance), hemochromatosis or copper overload conditions, autoimmune disorders, and patients on immunosuppressants or blood thinners
An NDA has been filed with the FDA
The takeaway is that current-day peptide use requires discernment