It mimics a hormone called GLP-1 that controls blood sugar levels in the body
Tiredness can result from reduced caloric intake due to appetite suppression, rapid weight loss, gastrointestinal symptoms causing dehydration and nutrient deficiencies, or hypoglycaemia when GLP-1 medications are combined with insulin or sulphonylureas
CrossRef Elevated adipose inflammation, but reduced hepatic triacylglycerol storage in diet-induced obese Plin4/ mice Atanaska Ivanova Doncheva, Ryoko Higa, Prabhat Khanal, Martine Villemo ksenvg Ingebrigtsen, Yuchuan Li, Shrikant Kolan, Pratibha Kolan, Ales Kvasnicka, Ingunn Jermstad, Shaista Khan, Bjrn Steen Sklhegg, Svein Olav Kolset, Hilde Nebb, Marit Hjorth, Fro Journal of Biological Chemistry .2026
2023 Oct;93(5):401-409
More people lost 5%, 10%, and 15% of their weight on tirzepatide
Gault VA, Flatt PR, Harriott P, Mooney MH, Bailey CJ, OHarte FP