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Permeation-enhancing and unique mucoadhesive properties help molecules absorb into mucosal tissue, potentially delivering greater drug absorption and increased contact time

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The cyclization step, involving the -amino group of lysine and -carboxy group of aspartic acid, was performed using an 8-fold excess of DCC as the coupling agent and 1-hydroxybenzotriazole (HOBt) as a racemization suppressant

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