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While these mechanisms can explain the protective effect that GLP-1 RA exposure had on the fracture risk of the exposed patients in our study, it is important to consider the fact that the findings mentioned were from studies primarily conducted on patients prescribed GLP-1 RA who had a diagnosis of T2DM, as this is what the drugs were originally FDA-approved to treat
The mechanism of action involves binding to GLP-1 receptors located throughout the body, including the pancreas, brain, and cardiovascular system
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Dosing Preferences Both treatments involve weekly injections, but the dosing schedules differ slightly
It also attenuates cardiac remodeling by reducing collagen deposition and cardiomyocyte apoptosis, while decreasing the expression of TGF-1 and phosphorylated-Smad3 [171]
Insurance Pre-Authorization: A Common Roadblock For patients using insurance, pre-authorization is often required before starting most prescription weight loss medications or procedures
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