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10.3389/fimmu.2015.00386 158 RosenstockJ.Aguilar-SalinasC.KleinE.NepalS.ListJ.ChenR.et al (2009b)

We believe that the mechanistic pathways uncovered here have potential for impact in the clinical context of IRI, for which no approved therapies currently exist

Because L-carnitine is absorbed via a specific sodium-dependent transporter in the small intestine (known as OCTN2) that can easily become saturated by large single doses, dividing the intake throughout the day maximizes overall intestinal absorption

4a, b), which was accompanied by reduction in body weight gain at 24 h and even 48 h (Fig