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Journal of Pharmacology and Experimental Therapeutics

2021 May 1;167:94-108 PMID: 33722625 22

According to its activity level the enzyme variants were classified in five types 23 , such as: Class 1: Deficiency of the enzyme with chronic non-spherlocytic-hemolytic anemia (CNSHA)

Always discuss new supplement regimens with your medical team to ensure they align safely with your current medications and specific metabolic needs

High-quality B-complex supplements providing methylated forms of folate (5-MTHF) and B12 (methylcobalamin) may offer advantages for individuals with genetic variations affecting B vitamin metabolism

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