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Rushing to higher concentrations before lower ones have demonstrated their effects leads to unnecessary escalation

The fundamental goal of antiseizure medications (ASMs) is to restore this balance involving a diverse range of molecular strategies

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Three things worth considering: - Normal-looking biomarkers on medication are not the same as metabolic health

Moreover, GLP-1 does not affect energy expenditure in humans [28] which means that this treatment does not compensate for the reduction in energy expenditure that is observed with weight loss, a phenomenon that again limits the weight loss associated with GLP-1 analogue treatment

This does not mean that a very brief increase in glutamate content, as shown in Figure 2 might not, at least partly, be derived from glycogen, which showed a simultaneous precipitous and large fall (Hertz et al., 2003)