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J., 3rd, et al

Key points in a shared decision-making strategy ( Figure ) include patient-centered communication to ensure that the patient who may be reluctant to discontinue the GLP-1 RA feels heard and like an equal contributor to the decision

In this Analysis, we searched for relevant literature on the effects of GLP-1RAs across a range of illnesses, gathering and describing the available pre-clinical and mechanistic (278 studies) and clinical (96 studies) evidence for cognitive disorders, substance-use disorders, psychotic disorders, mood and anxiety disorders, eating disorders, and others

Brand-name products remain expensive, and coverage has tightened

Both approaches are valid

Outcomes depend on adherence, baseline health, and lifestyle integration