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Kinetics, Pharmacokinetics, and Regulation of L-Carnitine and Acetyl-L-Carnitine Metabolism
A study by Newsome et al., designed to evaluate semaglutide as a potential treatment for Non-alcoholic Fatty Liver Disease (NAFLD)/Non-alcoholic Steatohepatitis (NASH), showed a dose dependent decrease in ALT levels, with maximal reductions occurring around week 28 and remaining stable thereafter [38]
The mechanisms through which GLP-1 receptor agonists may reduce inflammation are multifaceted and not yet fully understood
doi: 10.3389/fonc.2023.1089115 72 XieCZhuJJiangYChenJWangXGengSet al
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