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Large-scale randomised controlled trials (RCTs) of semaglutide, including the SUSTAIN and PIONEER trial programmes, have not demonstrated a statistically significant increase in pancreatic cancer incidence among participants receiving the drug compared to placebo or active comparators

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Pedersen IM, Kitada S, Schimmer A, Kim Y, Zapata JM, Charboneau L, Rassenti L, Andreeff M , Bennett F, Sporn MB, Liotta LD, Kipps TJ, Reed JC

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