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This condition commonly follows major physiological stressors, including rapid weight loss, caloric restriction, and nutritional deficiencies

Lee SD, Huang CY, Shu WT, Chen TH, Lin JA, Hsu HH et al (2006) Pro-inflammatory states and IGF-I levels in ischemic heart disease with low or high serum iron

Clinical data shows approximately 25-35% of total weight loss comes from lean mass in untrained individuals not optimizing protein or training

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Williams broke her silence about her weight loss journey, revealing she used medication to help her lose 31 pounds