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When Injectable GLP-1s May Be Preferred Despite orforglipron's convenience advantages, several scenarios favor injectable GLP-1 therapies: Patients requiring maximal weight loss: Injectable semaglutide 2.4 mg weekly produces approximately 15-17% weight loss, and tirzepatide can achieve 20-25% weight loss at maximal doses
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Common Side Effects of Semaglutide Most side effects associated with GLP-1 medications are gastrointestinal
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