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All authors read and approved the final draft of the manuscript

GLP-1 medications mimic natural hormones that regulate hunger, blood sugar, and energy balance

This analysis specifically in ARC POMC neurons revealed that leptin receptor-expressing and GLP-1R-expressing neurons are non-overlapping [153], which was confirmed in an independent study using in situ hybridization and transgenic reporter mice [154]

A 12-week cycle extends the optimization phase to 6 to 8 weeks before transitioning to maintenance

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