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They are usually injected subcutaneously and require consistent dosing to maintain biological activity

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Dosing mistakes are the most common, and most preventable, problem in peptide research

Some are approved for type 2 diabetes or chronic weight management

Female sex While the trial data does not provide a definitive gender breakdown for skin sensitivity specifically, studies on allodynia and dysesthesia across the GLP-1 class suggest women may be slightly more susceptible than men