Direct force can damage peptide structure and cause foaming
Mechanistically, Gln deprivation increases slug expression by triggering the ATF4 and MEK/ERK signaling pathways, thereby inducing EMT and promoting the metastasis of PDAC cells
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doi: 10.1038/ncomms11624 147 KollsJ
GLP-1 therapies are integrated into a broader regimen, and discontinuation is typically considered within the context of overall disease management