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GLP-1RAs are classified according to their structural and pharmacokinetic properties

Neuron 97, 12681283.E6.10.1016/j.neuron.2018.02.027 253 NiwaJ.YamadaS.IshigakiS.SoneJ.TakahashiM.KatsunoM.et al

Preservatives are typically added to sterile medications that come in multi-dose vials or pens

Mechanistically, GLP-1 signaling suppresses M1-associated genes while enhancing that of M2-related genes through activation of signal transducer and activator of transcription 3 (STAT3) (Wan and Sun, 2019)