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The role of UA as a predictor of the progression rate of multiple non-motor symptoms was also proven in some clinical trials [92, 93]
For clinicians used to watching kidney disease march forward despite treatment, these results were a massive shift
Patients experiencing these symptoms should discontinue their GLP-1 medication immediately and seek urgent medical evaluation
however, these are investigational trial doses and do not constitute approved prescribing information
Tirzepatide, meanwhile, is an established treatment with proven clinical outcomes and FDA-approved indications
PMID: 9186261
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