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The two bioactive forms of vitamin B 12 are methylcobalamin in cytosol and adenosylcobalamin in mitochondria

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The vitamin is then transferred to TC2, which serves as the circulating plasma transporter, hereditary defects in the production of TC2 and its receptor may produce functional deficiencies in B 12 and infantile megaloblastic anemia, and abnormal B 12 related biochemistry, even in some cases with normal blood B 12 levels

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AOD-9604's quality verification is more demanding than for a typical linear 16-mer because the intramolecular disulfide bond must be formed in the correct topology