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Research citations current as of June 2026
In the catalytic cycle of GPX4, the -SeH (the main active group of GPX4) is oxidized by the PLOOH to selenic acid (-SeOH), while G-SH can reduce -SeOH and further activates GPX4, releasing GS-SG to prevent GPX4 from being inactivated (Ingold et al., 2018)

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17 patients with eGFR 60 ml/min/1.73 m 2 received in a random order a single subcutaneous dose 1.2 mg liraglutide and placebo with subsequent 24 h blood pressure and natriuresis monitoring