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How GLP-1 helps insulin sensitivity GLP-1 receptor agonists improve insulin sensitivity rapidly, often before any weight loss occurs

If youre finding that days five, six, and seven of your weekly cycle bring back significant cravings or appetite comparable to what you felt before starting treatment, thats a strong signal your current dose has peaked in its effect for you

A more significant concern is the increased risk of hypoglycemia (low blood sugar), especially if other glucose-lowering medications are also being used

If reactions are bothersome, trying a single dose of cetirizine or loratadine 30 to 60 minutes before injection is a reasonable low-risk strategy

Twice a day and one capsule at each time after meal