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designed a US-triggered MnWO X nanosystem modified with PEG (termed MnWO X -PEG) to endow the capability of GSH-enhanced ROS ( 1 O 2 and OH) production for killing malignant tumors (Figure 6D) (Gong et al., 2019)

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Both the TfR and IR have been widely utilized to transport CNS targeting drugs across the BBB via the trojan horse strategy [24]