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Zepbound is a dual receptor agonist that targets both GLP-1 and GIP
The synthesis of the niacin-containing coenzymes, NAD and NADP, from the amino acid tryptophan, requires the FAD-dependent enzyme, kynurenine 3-monooxygenase
And it has many social, commercial and environmental determinants, requiring action in many sectors not only in the clinic. These other determinants of obesity, such as a food environment rich in high sugar, fat, and salt foods, mean that the global overweight or obese population is expected to reach 60% by 2050
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Cascone T, William Jr WN, Weissferdt A, Leung CH, Lin HY, Pataer A, Godoy M, Carter BW, Federico L, Reuben A, Khan AW, Dejima H, Cruz AF, Parra ER, Solis LM, Fujimoto J, Tran H, Moran C, Kalhor N, Fossella FV, Mott FE, Tsao AS, Blumenschein Jr G, Le X, Zhang J, Skoulidis F, Kurie J, Altan M, Lu C, Glisson B, Byers LA, Elamin Y, Mehran RJ, Rice DC, Walsh G, Hofstetter WL, Roth JA, Antonoff M, Kadara H, Haymaker C, Bernatchez C, Ajami NJ, Jenq RR, Sharma P, Allison J, Futreal A, Wargo JA, Wistuba II, Swisher SG , Lee JJ, Gibbons DL, Vaporciyan AA, Heymach JV, Sepesi B
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