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Yes, B12 supplementation is appropriate if deficiency is confirmed, and the MHRA recommends monitoring B12 levels in people on long-term metformin

When to Use Vitamin B12 vs Vitamin B Complex When Vitamin B12 Injections Are Most Appropriate Vitamin B12 injections are most appropriate when there is evidence or strong suspicion of vitamin B12 deficiency

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NAD+ (Nicotinamide Adenine Dinucleotide) NAD+ is a critical coenzyme involved in mitochondrial energy production and DNA repair

* The effect of oral cobalamin treatment in patients presenting with severe neurological manifestations has not yet been adequately documented