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Eight [percent] to 20% is what were seeing in [patients without cancer], and in our breast cancer population, we saw a more modest 5%

Decreasing inflammation can often make blood vessels work better and improve how blood flows

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A structured titration schedule for Mounjarostarting at the lowest dose (2.5 mg weekly for 4 weeks), then increasing to 5 mg, with further increases by 2.5 mg every 4 weeks or more as toleratedcan help minimise gastrointestinal side effects and associated volume depletion

Typically once weekly, though some protocols use twice-weekly dosing