doi: 10.1016/S2213-8587(25)00226-8 10 WaddenTABaileyTSBillingsLKDaviesMFriasJPKorolevaAet al
Resting metabolic rate, total daily energy expenditure, and metabolic adaptation 6 months and 24 months after bariatric surgery
Sarcopenia (muscle loss) due to rapid weight loss if measures to preserve muscle are not taken, including regular strength training, staying active, and eating a protein-rich diet
"Metabolic effects of tesamorelin, a growth hormone-releasing factor, in patients with HIV-associated abdominal fat accumulation: a randomized, double-blind, placebo-controlled trial." HIV Medicine , 11(5), 331340
Things To Know Mounjaro uses dual hormone technology targeting GIP and GLP-1 receptors simultaneously Trulicity focuses solely on the GLP-1 pathway for blood sugar control Both medications require once-weekly injections administered subcutaneously Mounjaro typically produces greater A1C reductions averaging 2.0% to 2.3% Trulicity has a longer track record with over 10 years of real-world use Weight loss tends to be more significant with Mounjaro due to its dual action Side effects for both primarily involve gastrointestinal symptoms Mounjaro is available in higher maximum doses than Trulicity How Mounjaro and Trulicity Work Differently The fundamental difference in how these medications function explains much of their varying results
Amylin receptor activation in the ventral tegmental area reduces motivated ingestive behavior