Most people find these effects diminish over time as the body adapts, but the initial adjustment period can be genuinely unpleasant
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Room temperature storage should be limited to brief periods onlytypically no longer than 30 minutes total during handling or travel
Mario-Suarez JE, Monedero-Recuero I, Pelaez-Laguno C: B12 vitamin deficiency and oral treatment
doi: 10.1016/S0022-3999(01)00315-4 Summary Keywords Sensewear armband, myalgic encephalomyelitis/chronic fatigue syndrome, vitamin B12 nasal drops, vitamin B12 serum concentration, RAND 36 questionnaire Citation van Campen CLMC, Riepma K and Visser FC (2019) Open Trial of Vitamin B12 Nasal Drops in Adults With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Comparison of Responders and Non-Responders
In cases where absorption is compromised, high oral doses or very high doses (such as 1,0002,000 mcg) of vitamin B12 may be required to correct deficiency, as these can sometimes be effective alternatives to injections
