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Numerous preclinical reports have highlighted the ability of curcumin to restore reduced GSH levels and the activities of GSH-related antioxidant enzymes in the myocardium after exposure to cardiotoxic factors, for example, DOX, I/R, diabetes, hyperthyroid conditions, and copper sulfate [184,185,186,187,188]

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But the federal agency warns that these unauthorized drugs, which are illegal, pose serious health risks, adding that it still needs to evaluate them for safety, efficacy, and quality. They have not been demonstrated, through scientific trials, to provide the health benefits that they claim, according to Health Canada in an April advisory

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Synergistic use can harness their strengths, though rigorous human trials are still needed

These trace minerals often become depleted during healing periods when demands increase