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Alogliptin: a review of its use in the management of type 2 diabetes mellitus

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262 The accumulation of amyloid fibrils in the cardiac extracellular matrix induces myocardial stiffness and conduction disturbances, leading to clinical manifestations such as HF and arrhythmias

This was the case of 3 women, one of whom even developed holes in the bowel (perforation) [71+, 72+, 73+]