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Metabolomics and lipidomics approaches have provided insightful evidence of altered metabolic pathways in NAFLD and NASH
In this case, GSH levels are well below the normal concentration, and therefore there is no feedback inhibition of GCL
Identification of nicotinamide Nmethyltransferase as a promising therapeutic target against diabetic cardiomyopathy
Finally, in mutant analysis, only mutations of Cys residues 226 and 613 resulted in defective induction of ARE activity in the presence of Cyss (Fig
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