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Mendelian randomization analysis suggests a potential genetic link between increased opioid use and the risk of major depressive disorder (MDD) and anxiety-related disorders 62
K.et al (2016)
4 This improvement has been corroborated in other studies both in patients with ASD and other neurological conditions
This neurodegeneration is accompanied by the formation of characteristic Lewy bodies, which are intracellular inclusions composed largely of aggregated and misfolded -synuclein ( This degeneration of dopaminergic neurons is strongly linked to the generation of reactive oxygen species and oxidative stress as well as mitochondrial dysfunction, neuroinflammation, and aging (Smeyne and Smeyne, 2013)
Unlike traditional pharmacology, which studies a single compound or a single target, omics can capture the global effects of traditional Chinese medicine from a systematic perspective
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