Its mechanism of action involves reducing hepatic glucose production, decreasing intestinal glucose absorption, and improving insulin sensitivity in peripheral tissues
These effects are generally mild to moderate in severity and tend to diminish over time as the body adjusts to the medication
These may be mild or severe and can be treated with over-the-counter pain relievers
When taken once a week, it can lead to significant weight loss over time
You should stop taking Wegovy and contact your GP or seek urgent medical advice if you experience: Severe or persistent abdominal pain , particularly if localised to the upper abdomen or accompanied by back pain and/or vomiting (potential signs of pancreatitis, a rare but serious side effect) Persistent vomiting that prevents you from keeping down fluids or medications Signs of dehydration , including dark urine, dizziness, or reduced urination Blood in vomit or stools , or black, tarry stools (potential indicators of gastrointestinal bleeding) Severe heartburn or difficulty swallowing that does not respond to antacids Progressive difficulty swallowing (dysphagia) Symptoms of gallbladder disease , such as pain in the upper right abdomen, particularly after eating fatty meals You should also consult your pharmacist or GP if you find yourself using antacids daily for more than two weeks

however, compounds that exert additional effects, such as regulation of energy expenditure, are expected to act with larger efficiency