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It binds to GHRH receptors on pituitary somatotroph cells, stimulating the synthesis and secretion of endogenous growth hormone in a natural pulsatile pattern (1)

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But more clinical studies are still needed to confirm its efficacy and safety

Doctors usually begin with a low dose of semaglutide, such as 0.25 mg, given once a week as a subcutaneous injection

However, injectable forms like Tad 600mg provide faster and more potent effects

Renal effects, including acute kidney injury, have been reported rarely in post-marketing surveillance, typically in the context of severe gastrointestinal adverse effects leading to dehydration