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Studies from the STEP trials showed that participants on semaglutide lost a meaningful proportion of their total weight loss as lean mass, with estimates ranging from 25 to 40 percent of total weight lost coming from non-fat tissue depending on activity level and protein intake

Behavioural factors also play a crucial role in weight plateaus

The arrival of GLP-1 drugs is not a panacea for obesity

By lowering glucagon and raising insulin, it does this

Research documents CNS-mediated mechanisms distinct from peripheral vascular pathways

Type 2 diabetes: agreeing my blood glucose (HbA1c) target patient decision aid (NG28)