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The date of first use should be recorded on the vial, and the medication should be discarded after the specified period following initial puncture, typically 28 days, even if medication remains and the beyond-use date has not been reached

[16] Einarson TR, Acs A, Ludwig C, Panton UH

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The peptides cyclic heptapeptide structure confers increased metabolic stability and receptor affinity compared to native -MSH, extending its bioactivity in systemic models