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For 80%-90% of people with systemic mastocytosis, a mutation in the KIT gene is the cause

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Patients on antithyroid medications (PTU or methimazole) need thyroid function monitored more frequently during GLP-1 therapy

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Synephrine has also been linked to increased heart rate and blood pressure, raising safety concerns

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Regional Analysis North America Leading the GLP-1 Receptor Agonist Market North America accounted for the largest revenue share of 49.7% , supported by the high prevalence of type 2 diabetes and obesity, a developed healthcare system, and favorable reimbursement structures

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