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Be patient, as noticeable effects may take time

POTENT ANTI-INFLAMMATORY EFFECTS

A 2.5 mg target dose is 2,500 mcg

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Progestogen-only pill worsened the HS symptoms, while beneficial effects are exerted for female patients by combined oral contraceptive pills, and anti-androgen agents, such as cyproterone acetate, a competitive antagonist at the androgen receptor, finasteride, an inhibitor of type 5-reductase, the enzyme converting testosterone and its active metabolite 5-dihydrotestosterone, or spironolactone, a potassium-sparing diuretic acting as competitive aldosterone receptor antagonist and exerting weak anti-androgenic effects [82]