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They complement each other by improving skin brightness, strengthening the barrier, and reducing pigmentation

doi:10.1097/XCE.0000000000000223 Terashvili M, Bosnjak ZJ

The proatherosclerotic function of indoleamine 2, 3-dioxygenase 1 in the developmental stage of atherosclerosis

If taste changes persist or worsen, further evaluation may be necessary to rule out other underlying causes such as medication interactions, nutritional deficiencies, or dental problems

JoAnn Manson, chief of the division of preventive medicine at Brigham and Womens Hospital in Boston and professor of medicine at Harvard Medical School

The downsides: Expensive, no evidence of efficacy