An additional open question is whether propagating ferroptotic injury contains reversible intermediate states before reaching tissue-scale collapse or whether spread proceeds as a strictly irreversible process once initiated
10.1038/nature03434 310 Nakagawa T., Shimizu S., Watanabe T., Yamaguchi O., Otsu K., Yamagata H., Inohara H., Kubo T., Tsujimoto Y., Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
There is no good quality clinical evidence to suggest that CYP450 polymorphisms influence paracetamol toxicity (see Fig
Antioxidants naturally become a topic of interest, specifically the "master antioxidant" known as glutathione
Amino acid sensing in dietary-restriction-mediated longevity: Roles of signal-transducing kinases Gcn2 and tor
Dong L-H, Li L, Song Y, Duan Z-L, Sun S-G, Lin Y-L, et al