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Most likely, yes

Gaullier JM et al

Spatial buffering of potassium ions in brain extracellular space

This entails an increase in the release of stress hormones like glucocorticoids and catecholamines ( Polycystic ovary syndrome is another disease entity in which stress plays a role in the pathogenesis ( 4 Connection of chronic stress and oxidative stress Oxidative stress is a condition of the body in which there is a significantly increased concentration of reactive oxygen species relative to antioxidant substances ( There are two sources of reactive oxygen species: endogenous and exogenous ( The main components of oxidative stress are reactive oxygen species and reactive nitrogen species ( Many studies confirm the correlation between exposure to chronic stress and the occurrence of oxidative stress and elevated markers of oxidative stress ( Studies using animals show that the long-term effects of cortisol can affect individual markers of oxidative stress ( Another animal study evaluated the effects of chronic stress induced by immobilizing an animal for 21 days on the activity of oxidative stress-related indicators

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