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This substance can also reduce the oxidative stress (Lee et al., 2008) on SH-SY5Y (human dopaminergic neuron cells) by controlling the upregulation of Bax and the downregulation of Bcl-2, and reduce mitochondrial membrane potential by reducing reactive oxygen species

Turk J Med Sci 49:10471053

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Discussion on the relationship between gut microbiota and glioma through Mendelian randomization test based on the brain gut axis

and once you get into the centenarian club, that appears to be almost exclusively genetic

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