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Multi-Pathway ECM Remodeling Anti-Inflammatory Mechanism of Action Primary GHK-Cu: TGF- / LOX / Gene Expression ECM Remodeling & Gene Expression Modulation GHK-Cu (50mg) upregulates collagen synthesis, activates lysyl oxidase, and modulates over 4,048 genes identified by Connectivity Map analysis

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Proc Natl Acad Sci U S A 96:760765 Takeda Y, Amano A, Noma A, Nakamura Y, Fujimoto S, Inagaki N (2011) Systems analysis of GLP-1 receptor signaling in pancreatic -cells

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