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Images were captured via laser scanning confocal microscopy (LSCM, Olympus FV3000) and analyzed using the ImageJ software

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The delayed gastric emptying effect is primarily mediated through GLP-1 receptor activation and contributes to increased satiety and reduced caloric intake, which are beneficial for weight management

As OxS plays an important role in PSC activation and pancreatic fibrosis, we hypothesized that high glucose could stimulate pancreatic cells to produce excess ROS and activate PSCs, that induce pancreatic fibrosis and ultimately lead to -cell failure

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